Glioblastoma Multiforme

• GBM represent 15% of brain tumors

• 3.2 cases per 100,000 population

• Median Survival Without Treatment-3 Months

• Median Survival With Treatment-1- 2 years

• Low quality of life

• Etiology-Unknown

• Current Standard of Care– Maximal surgical resection followed by 6 weeks of radiotherapy,

      together with concomitant chemotherapy with TMZ. Once            chemoradiotherapy is complete, a minimum of 6 months of          adjuvant treatment with TMZ is started

• Approximate Cost to Health Care System~$100 –250K/Year/Patient (Raizer 2014)