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Clinical Indications

 Glioblastoma Multiforme

  • GBM represent 15% of brain tumors

  • 3.2 cases per 100,000 population

  • Median Survival Without Treatment-3 Months

  • Median Survival With Treatment-1- 2 years

  • Low quality of life

  • Etiology-Unknown

  • Current Standard of Care– Maximal surgical resection followed by 6 weeks of radiotherapy,

      together with concomitant chemotherapy with TMZ. Once            chemoradiotherapy is complete, a minimum of 6 months of          adjuvant treatment with TMZ is started

  • Approximate Cost to Health Care System~$100 –250K/Year/Patient (Raizer 2014)

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